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Syntheses of defined sulfated oligohyaluronans reveal structural effects, diversity and thermodynamics of GAG–protein binding
Binding of sulfated glycosaminoglycans (GAG) to a wide spectrum of extracellular regulatory proteins is crucial for physiological processes such as cell growth, migration, tissue homeostasis and repair. Thus, GAG derivatives exhibit great relevance in the development of innovative biomaterials for t...
Autores principales: | Köhling, Sebastian, Blaszkiewicz, Joanna, Ruiz-Gómez, Gloria, Fernández-Bachiller, María Isabel, Lemmnitzer, Katharina, Panitz, Nydia, Beck-Sickinger, Annette G., Schiller, Jürgen, Pisabarro, M. Teresa, Rademann, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346292/ https://www.ncbi.nlm.nih.gov/pubmed/30774881 http://dx.doi.org/10.1039/c8sc03649g |
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