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The associations of DNA methylation alterations in oxidative stress-related genes with cancer incidence and mortality outcomes: a population-based cohort study

BACKGROUND: Reactive oxygen species may be involved in epigenetic gene activation or silencing. We aimed to identify CpG sites, at which DNA methylation is related to urinary 8-isoprostane levels (biomarker of lipid peroxidation) and cancer or mortality outcomes. This investigation was based on a Ge...

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Detalles Bibliográficos
Autores principales: Gào, Xīn, Zhang, Yan, Burwinkel, Barbara, Xuan, Yang, Holleczek, Bernd, Brenner, Hermann, Schöttker, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346508/
https://www.ncbi.nlm.nih.gov/pubmed/30678711
http://dx.doi.org/10.1186/s13148-018-0604-y