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Absence of endothelial α5β1 integrin triggers early onset of experimental autoimmune encephalomyelitis due to reduced vascular remodeling and compromised vascular integrity

Early in the development of multiple sclerosis (MS) and its mouse model experimental autoimmune encephalomyelitis (EAE), vascular integrity is compromised. This is accompanied by a marked vascular remodeling response, though it is currently unclear whether this is an adaptive vascular repair mechani...

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Detalles Bibliográficos
Autores principales: Kant, Ravi, Halder, Sebok K., Bix, Gregory J., Milner, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346510/
https://www.ncbi.nlm.nih.gov/pubmed/30678721
http://dx.doi.org/10.1186/s40478-019-0659-9