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Exogenous supplement of N-acetylneuraminic acid improves macrophage reverse cholesterol transport in apolipoprotein E-deficient mice

BACKGROUND: N-acetylneuraminic acid (NANA) is the major form of sialic acid in mammals, and the plasma NANA level is increased in patients with cardiovascular diseases. Exogenous supplement of NANA has been demonstrated to reduce hyperlipidaemia and the formation of atherosclerotic lesions; however,...

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Detalles Bibliográficos
Autores principales: Hou, Pengbo, Hu, Shumei, Wang, Jin, Yang, Zixun, Yin, Jiayu, Zhou, Guanghai, Guo, Shoudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346517/
https://www.ncbi.nlm.nih.gov/pubmed/30678697
http://dx.doi.org/10.1186/s12944-019-0971-1