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Current perspectives on mechanisms of ribonucleotide incorporation and processing in mammalian DNA
Ribonucleotides, which are RNA precursors, are often incorporated into DNA during replication. Although embedded ribonucleotides in the genome are efficiently removed by canonical ribonucleotide excision repair (RER), inactivation of RER causes genomic ribonucleotide accumulation, leading to various...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346524/ https://www.ncbi.nlm.nih.gov/pubmed/30700998 http://dx.doi.org/10.1186/s41021-019-0118-7 |