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CXCL12/CXCR4 promotes inflammation-driven colorectal cancer progression through activation of RhoA signaling by sponging miR-133a-3p

BACKGROUND: Activation of CXCL12/CXCR4 axis has been found to be associated with invasion and metastasis in many cancers. However, the underlying mechanism remains elusive. Increasing data highlight that non-coding RNAs are linked to CRC progression. METHODS: The effects of CXCR4 were investigated u...

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Detalles Bibliográficos
Autores principales: Yu, Xinfeng, Wang, Dong, Wang, Xiaohui, Sun, Shiyue, Zhang, Yuhang, Wang, Shuqing, Miao, Rongrong, Xu, Xiaoxue, Qu, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346552/
https://www.ncbi.nlm.nih.gov/pubmed/30678736
http://dx.doi.org/10.1186/s13046-018-1014-x