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Mechanism and regulation of DNA damage recognition in nucleotide excision repair

Nucleotide excision repair (NER) is a versatile DNA repair pathway, which can remove an extremely broad range of base lesions from the genome. In mammalian global genomic NER, the XPC protein complex initiates the repair reaction by recognizing sites of DNA damage, and this depends on detection of d...

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Detalles Bibliográficos
Autores principales: Kusakabe, Masayuki, Onishi, Yuki, Tada, Haruto, Kurihara, Fumika, Kusao, Kanako, Furukawa, Mari, Iwai, Shigenori, Yokoi, Masayuki, Sakai, Wataru, Sugasawa, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346561/
https://www.ncbi.nlm.nih.gov/pubmed/30700997
http://dx.doi.org/10.1186/s41021-019-0119-6