Extracellular overproduction of E7 oncoprotein of Iranian human papillomavirus type 16 by genetically engineered Lactococcus lactis

BACKGROUND: We aimed at constructing Lactococcus lactis strains expressing HPV-16 recombinant E7 (rE7) oncoprotein and examining its overproduction ability followed by optimizing batch and fed-batch fermentations. Thereafter, in order to assess the immunogenicity of recombinant L. lactis cells, C57B...

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Detalles Bibliográficos
Autores principales: Mohseni, Amir Hossein, Taghinezhad-S, Sedigheh, Keyvani, Hossein, Razavilar, Vadood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346575/
https://www.ncbi.nlm.nih.gov/pubmed/30678667
http://dx.doi.org/10.1186/s12896-019-0499-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346575/
https://www.ncbi.nlm.nih.gov/pubmed/30678667
http://dx.doi.org/10.1186/s12896-019-0499-5

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