Cargando…

A Novel Vaccine Strategy Employing Serologically Different Chimpanzee Adenoviral Vectors for the Prevention of HIV-1 and HCV Coinfection

Background: Nearly 3 million people worldwide are coinfected with HIV and HCV. Affordable strategies for prevention are needed. We developed a novel vaccination regimen involving replication-defective and serologically distinct chimpanzee adenovirus (ChAd3, ChAd63) vector priming followed by modifie...

Descripción completa

Detalles Bibliográficos
Autores principales: Hartnell, Felicity, Brown, Anthony, Capone, Stefania, Kopycinski, Jakub, Bliss, Carly, Makvandi-Nejad, Shokouh, Swadling, Leo, Ghaffari, Emma, Cicconi, Paola, Del Sorbo, Mariarosaria, Sbrocchi, Roberta, Esposito, Ilaria, Vassilev, Ventzislav, Marriott, Paula, Gardiner, Clair M., Bannan, Ciaran, Bergin, Colm, Hoffmann, Matthias, Turner, Bethany, Nicosia, Alfredo, Folgori, Antonella, Hanke, Tomáš, Barnes, Eleanor, Dorrell, Lucy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346592/
https://www.ncbi.nlm.nih.gov/pubmed/30713538
http://dx.doi.org/10.3389/fimmu.2018.03175