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Gene mutations in a Han Chinese Alzheimer's disease cohort

OBJECTIVE: Alzheimer's disease (AD) is the most common form of dementia characterized by memory loss at disease onset. The gene mutations in the amyloid precursor protein (APP), presenilin 1 (PSEN1), and presenilin 2 (PSEN2) are the frequent causes of AD. However, the clinical and genetic featu...

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Detalles Bibliográficos
Autores principales: Ma, Limin, Zhang, Jiewen, Shi, Yingying, Wang, Wan, Ren, Zhixia, Xia, Mingrong, Zhang, Yuanxing, Yang, Miaomiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346667/
https://www.ncbi.nlm.nih.gov/pubmed/30549411
http://dx.doi.org/10.1002/brb3.1180