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Anti-N-Methyl-D-Aspartic Acid Receptor 2 (Anti-NR2) Antibody in Neuropsychiatric Lupus Serum Damages the Blood–Brain Barrier and Enters the Brain

BACKGROUND: Brain microvessel endothelial cells constitute an important component in the blood-brain barrier. Cell-culture-based models of the blood-brain barrier (BBB) have been extensively applied in pharmacology, pathology and physiology. This study investigated effects of anti-N-methyl-D-asparti...

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Detalles Bibliográficos
Autores principales: Wang, Jing-Yuan, Zhao, Yin-Huan, Zhang, Ji-Hui, Lei, Hong-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346811/
https://www.ncbi.nlm.nih.gov/pubmed/30657743
http://dx.doi.org/10.12659/MSM.912389