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Prasugrel and Acquired Thrombotic Thrombocytopenic Purpura Associated with ADAMTS13 Activity Deficiency

We report a case of a 64-year-old man who, 44 days after starting treatment with prasugrel, presented with severe thrombocytopenia, anaemia, renal failure, and severe ADAMTS13 activity deficiency, along with a high titer of autoantibodies to this protease. LEARNING POINTS: Drug-induced TTP is a rare...

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Detalles Bibliográficos
Autores principales: Lopez, Yanet Parodis, Gonzalez, Nery Sablon, Villalba, Noel Lorenzo, Galvan, Rafael Camacho, Perez, Jose Carlos Rodriguez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346962/
https://www.ncbi.nlm.nih.gov/pubmed/30755885
http://dx.doi.org/10.12890/2016_000446