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Effect of Sec61 interaction with Mpd1 on endoplasmic reticulum-associated degradation
Proteins that misfold in the endoplasmic reticulum (ER) are transported back to the cytosol for ER-associated degradation (ERAD). The Sec61 channel is one of the candidates for the retrograde transport conduit. Channel opening from the ER lumen must be triggered by ERAD factors and substrates. Here...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347170/ https://www.ncbi.nlm.nih.gov/pubmed/30682149 http://dx.doi.org/10.1371/journal.pone.0211180 |