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Effect of Sec61 interaction with Mpd1 on endoplasmic reticulum-associated degradation

Proteins that misfold in the endoplasmic reticulum (ER) are transported back to the cytosol for ER-associated degradation (ERAD). The Sec61 channel is one of the candidates for the retrograde transport conduit. Channel opening from the ER lumen must be triggered by ERAD factors and substrates. Here...

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Detalles Bibliográficos
Autores principales:	Pereira, Fabio, Rettel, Mandy, Stein, Frank, Savitski, Mikhail M., Collinson, Ian, Römisch, Karin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347170/ https://www.ncbi.nlm.nih.gov/pubmed/30682149 http://dx.doi.org/10.1371/journal.pone.0211180

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