Interaction of two antitumor peptides with membrane lipids – Influence of phosphatidylserine and cholesterol on specificity for melanoma cells

R-DIM-P-LF11-322 and DIM-LF11-318, derived from the cationic human host defense peptide lactoferricin show antitumor activity against human melanoma. While R-DIM-P-LF11-322 interacts specifically with cancer cells, the non-specific DIM-LF11-318 exhibits as well activity against non-neoplastic cells....

Descripción completa

Detalles Bibliográficos
Autores principales: Wodlej, Christina, Riedl, Sabrina, Rinner, Beate, Leber, Regina, Drechsler, Carina, Voelker, Dennis R., Choi, Jae-Yeon, Lohner, Karl, Zweytick, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347193/
https://www.ncbi.nlm.nih.gov/pubmed/30682171
http://dx.doi.org/10.1371/journal.pone.0211187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347193/
https://www.ncbi.nlm.nih.gov/pubmed/30682171
http://dx.doi.org/10.1371/journal.pone.0211187

Ejemplares similares