HIV-1 infection increases microRNAs that inhibit Dicer1, HRB and HIV-EP2, thereby reducing viral replication

HIV-1 is the causative agent of AIDS (Autoimmune Deficiency Syndrome). HIV-1 infection results in systemic CD4(+) T cell depletion, thereby impairing cell-mediated immunity. MicroRNAs are short (~22 nucleotides long), endogenous single-stranded RNA molecules that regulate gene expression by binding...

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Detalles Bibliográficos
Autores principales: Modai, Shira, Farberov, Luba, Herzig, Eytan, Isakov, Ofer, Hizi, Amnon, Shomron, Noam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347224/
https://www.ncbi.nlm.nih.gov/pubmed/30682089
http://dx.doi.org/10.1371/journal.pone.0211111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347224/
https://www.ncbi.nlm.nih.gov/pubmed/30682089
http://dx.doi.org/10.1371/journal.pone.0211111

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