Iba-1(-)/CD68(+) microglia are a prominent feature of age-associated deep subcortical white matter lesions

Deep subcortical lesions (DSCL) of the brain, are present in ~60% of the ageing population, and are linked to cognitive decline and depression. DSCL are associated with demyelination, blood brain barrier (BBB) dysfunction, and microgliosis. Microglia are the main immune cell of the brain. Under phys...

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Detalles Bibliográficos
Autores principales: Waller, Rachel, Baxter, Lynne, Fillingham, Daniel J., Coelho, Santiago, Pozo, Jose M., Mozumder, Meghdoot, Frangi, Alejandro F., Ince, Paul G., Simpson, Julie E., Highley, J. Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347230/
https://www.ncbi.nlm.nih.gov/pubmed/30682074
http://dx.doi.org/10.1371/journal.pone.0210888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347230/
https://www.ncbi.nlm.nih.gov/pubmed/30682074
http://dx.doi.org/10.1371/journal.pone.0210888

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