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Deterministic column subset selection for single-cell RNA-Seq

Analysis of single-cell RNA sequencing (scRNA-Seq) data often involves filtering out uninteresting or poorly measured genes and dimensionality reduction to reduce noise and simplify data visualization. However, techniques such as principal components analysis (PCA) fail to preserve non-negativity an...

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Detalles Bibliográficos
Autores principales: McCurdy, Shannon R., Ntranos, Vasilis, Pachter, Lior
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347249/
https://www.ncbi.nlm.nih.gov/pubmed/30682053
http://dx.doi.org/10.1371/journal.pone.0210571