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Accumulation of exhausted CD8+ T cells in extramammary Paget’s disease

Cancer immunotherapy has highlighted the clinical relevance of enhancing anti-tumor response of CD8+ T cells in several cancer types. Little is known, however, about the involvement of the immune system in extramammary Paget’s disease (EMPD). We examined the cytotoxicity and the effector functions o...

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Detalles Bibliográficos
Autores principales: Iga, Natsuko, Otsuka, Atsushi, Yamamoto, Yosuke, Nakashima, Chisa, Honda, Tetsuya, Kitoh, Akihiko, Nakajima, Saeko, Egawa, Gyohei, Nomura, Takashi, Dainichi, Teruki, Matsushita, Shigeto, Tanizaki, Hideaki, Yamamoto, Yuki, Funakoshi, Takeru, Fujisawa, Yasuhiro, Fujimura, Taku, Hata, Hiroo, Ishida, Yoshihiro, Kabashima, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347258/
https://www.ncbi.nlm.nih.gov/pubmed/30682105
http://dx.doi.org/10.1371/journal.pone.0211135