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Accumulation of exhausted CD8+ T cells in extramammary Paget’s disease
Cancer immunotherapy has highlighted the clinical relevance of enhancing anti-tumor response of CD8+ T cells in several cancer types. Little is known, however, about the involvement of the immune system in extramammary Paget’s disease (EMPD). We examined the cytotoxicity and the effector functions o...
Autores principales: | Iga, Natsuko, Otsuka, Atsushi, Yamamoto, Yosuke, Nakashima, Chisa, Honda, Tetsuya, Kitoh, Akihiko, Nakajima, Saeko, Egawa, Gyohei, Nomura, Takashi, Dainichi, Teruki, Matsushita, Shigeto, Tanizaki, Hideaki, Yamamoto, Yuki, Funakoshi, Takeru, Fujisawa, Yasuhiro, Fujimura, Taku, Hata, Hiroo, Ishida, Yoshihiro, Kabashima, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347258/ https://www.ncbi.nlm.nih.gov/pubmed/30682105 http://dx.doi.org/10.1371/journal.pone.0211135 |
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