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Amino acid permeases in Cryptococcus neoformans are required for high temperature growth and virulence; and are regulated by Ras signaling

Cryptococcosis is an Invasive Fungal Infection (IFI) caused by Cryptococcus neoformans, mainly in immunocompromised patients. Therapeutic failure due to pathogen drug resistance, treatment inconstancy and few antifungal options is a problem. The study of amino acid biosynthesis and uptake represents...

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Detalles Bibliográficos
Autores principales: Calvete, Crislaine Lambiase, Martho, Kevin Felipe, Felizardo, Gabrielle, Paes, Alexandre, Nunes, João Miguel, Ferreira, Camila Oliveira, Vallim, Marcelo A., Pascon, Renata C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347259/
https://www.ncbi.nlm.nih.gov/pubmed/30682168
http://dx.doi.org/10.1371/journal.pone.0211393