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Amino acid permeases in Cryptococcus neoformans are required for high temperature growth and virulence; and are regulated by Ras signaling
Cryptococcosis is an Invasive Fungal Infection (IFI) caused by Cryptococcus neoformans, mainly in immunocompromised patients. Therapeutic failure due to pathogen drug resistance, treatment inconstancy and few antifungal options is a problem. The study of amino acid biosynthesis and uptake represents...
Autores principales: | Calvete, Crislaine Lambiase, Martho, Kevin Felipe, Felizardo, Gabrielle, Paes, Alexandre, Nunes, João Miguel, Ferreira, Camila Oliveira, Vallim, Marcelo A., Pascon, Renata C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347259/ https://www.ncbi.nlm.nih.gov/pubmed/30682168 http://dx.doi.org/10.1371/journal.pone.0211393 |
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