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Non-alcoholic fatty liver disease is associated with dysregulated bile acid synthesis and diarrhea: A prospective observational study

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) may be associated with changes in bile acid (BA) metabolism. Hepatic BA production, measured by serum levels of the precursor 7α-hydroxy-4-cholesten-3-one (C4), is regulated by the farnesoid-X-receptor (FXR)-dependent ileal hormone fibroblast gro...

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Detalles Bibliográficos
Autores principales: Appleby, Richard N., Moghul, Iman, Khan, Shahid, Yee, Michael, Manousou, Pinelope, Neal, Tracy Dew, Walters, Julian R. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347262/
https://www.ncbi.nlm.nih.gov/pubmed/30682184
http://dx.doi.org/10.1371/journal.pone.0211348