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Tobramycin reduces key virulence determinants in the proteome of Pseudomonas aeruginosa outer membrane vesicles

Tobramycin is commonly used to treat Pseudomonas aeruginosa lung infections in patients with Cystic Fibrosis (CF). Tobramycin treatment leads to increased lung function and fewer clinical exacerbations in CF patients, and modestly reduces the density of P. aeruginosa in the lungs. P. aeruginosa resi...

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Detalles Bibliográficos
Autores principales: Koeppen, Katja, Barnaby, Roxanna, Jackson, Angelyca A., Gerber, Scott A., Hogan, Deborah A., Stanton, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347270/
https://www.ncbi.nlm.nih.gov/pubmed/30682135
http://dx.doi.org/10.1371/journal.pone.0211290