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Dissecting a novel allosteric mechanism of cruzain: A computer-aided approach
Trypanosoma cruzi is the causative agent of Chagas disease, a neglected infection affecting millions of people in tropical regions. There are several chemotherapeutic agents for the treatment of this disease, but most of them are highly toxic and generate resistance. Currently, the development of al...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347273/ https://www.ncbi.nlm.nih.gov/pubmed/30682119 http://dx.doi.org/10.1371/journal.pone.0211227 |