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miR-15a/miR-16-1 expression inversely correlates with cyclin D1 levels in Men1 pituitary NETs

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterised by the combined occurrence of parathyroid, pituitary and pancreatic islet tumours, and is due to mutations of the MEN1 gene, which encodes the tumour suppressor protein menin. Menin has multiple roles in genom...

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Detalles Bibliográficos
Autores principales: Lines, K E, Newey, P J, Yates, C J, Stevenson, M, Dyar, R, Walls, G V, Bowl, M R, Thakker, R V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347280/
https://www.ncbi.nlm.nih.gov/pubmed/30389902
http://dx.doi.org/10.1530/JOE-18-0278