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Oncogenic kinases and perturbations in protein synthesis machinery and energetics in neoplasia

Notwithstanding that metabolic perturbations and dysregulated protein synthesis are salient features of cancer, the mechanism underlying coordination of cellular energy balance with mRNA translation (which is the most energy consuming process in the cell) is poorly understood. In this review, we foc...

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Detalles Bibliográficos
Autores principales: Uchenunu, Oro, Pollak, Michael, Topisirovic, Ivan, Hulea, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347283/
https://www.ncbi.nlm.nih.gov/pubmed/30072418
http://dx.doi.org/10.1530/JME-18-0058