Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation

Hsp104 is a ring-forming, ATP-driven molecular machine that recovers functional protein from both stress-denatured and amyloid-forming aggregates. Although Hsp104 shares a common architecture with Clp/Hsp100 protein unfoldases, different and seemingly conflicting 3D structures have been reported. Ex...

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Detalles Bibliográficos
Autores principales: Lee, Sukyeong, Roh, Soung Hun, Lee, Jungsoon, Sung, Nuri, Liu, Jun, Tsai, Francis T.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347426/
https://www.ncbi.nlm.nih.gov/pubmed/30605683
http://dx.doi.org/10.1016/j.celrep.2018.12.037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347426/
https://www.ncbi.nlm.nih.gov/pubmed/30605683
http://dx.doi.org/10.1016/j.celrep.2018.12.037

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