Cargando…
Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation
Hsp104 is a ring-forming, ATP-driven molecular machine that recovers functional protein from both stress-denatured and amyloid-forming aggregates. Although Hsp104 shares a common architecture with Clp/Hsp100 protein unfoldases, different and seemingly conflicting 3D structures have been reported. Ex...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347426/ https://www.ncbi.nlm.nih.gov/pubmed/30605683 http://dx.doi.org/10.1016/j.celrep.2018.12.037 |