Streamlining the Chemoenzymatic Synthesis of Complex N-Glycans by a Stop and Go Strategy

Contemporary chemoenzymatic approaches can provide highly complex multi-antennary N-linked glycans. These procedures are, however, very demanding and typically involve as many as 100 chemical steps to prepare advanced intermediates that can be diversified by glycosyltransferases in a branch selectiv...

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Detalles Bibliográficos
Autores principales: Liu, Lin, Prudden, Anthony R., Capicciotti, Chantelle J., Bosman, Gerlof P., Yang, Jeong-Yeh, Chapla, Digantkumar G., Moremen, Kelley W., Boons, Geert-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347513/
https://www.ncbi.nlm.nih.gov/pubmed/30532014
http://dx.doi.org/10.1038/s41557-018-0188-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347513/
https://www.ncbi.nlm.nih.gov/pubmed/30532014
http://dx.doi.org/10.1038/s41557-018-0188-3

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