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Insights From Deep Sequencing of the HBV Genome—Unique, Tiny, and Misunderstood

Hepatitis B virus (HBV) is a unique, tiny, partially double-stranded, reverse-transcribing DNA virus with proteins encoded by multiple overlapping reading frames. The substitution rate is surprisingly high for a DNA virus, but lower than that of other reverse transcribing organisms. More than 260 mi...

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Detalles Bibliográficos
Autores principales: McNaughton, Anna L., D’Arienzo, Valentina, Ansari, M. Azim, Lumley, Sheila F., Littlejohn, Margaret, Revill, Peter, McKeating, Jane A., Matthews, Philippa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: by the AGA Institute. Published by Elsevier Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347571/
https://www.ncbi.nlm.nih.gov/pubmed/30268787
http://dx.doi.org/10.1053/j.gastro.2018.07.058