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AAV2.7m8 is a powerful viral vector for inner ear gene therapy

Adeno-associated virus (AAV) has been successfully used to deliver gene therapy to improve auditory function in mouse models of hereditary hearing loss. Many forms of hereditary hearing loss have mutations which affect the cochlear hair cells, the mechanosensory cells which allow for sound detection...

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Detalles Bibliográficos
Autores principales: Isgrig, Kevin, McDougald, Devin S., Zhu, Jianliang, Wang, Hong Jun, Bennett, Jean, Chien, Wade W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347594/
https://www.ncbi.nlm.nih.gov/pubmed/30683875
http://dx.doi.org/10.1038/s41467-018-08243-1