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Neuropilin-1-mediated pruning of corticospinal tract fibers is required for motor recovery after spinal cord injury

Following incomplete spinal cord injury (SCI), reorganization of the corticospinal tract (CST) contributes to spontaneous motor recovery. Axotomized CST fibers form collaterals and make synapses with interneurons, followed by pruning of excess fibers. Although axonal pruning is involved in refinemen...

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Detalles Bibliográficos
Autores principales: Nakanishi, Toru, Fujita, Yuki, Yamashita, Toshihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347615/
https://www.ncbi.nlm.nih.gov/pubmed/30683854
http://dx.doi.org/10.1038/s41419-019-1338-2