The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma

MicroRNA deregulation is a consistent feature of glioblastoma, yet the biological effect of each single gene is generally modest, and therapeutically negligible. Here we describe a module of microRNAs, constituted by miR-124, miR-128 and miR-137, which are co-expressed during neuronal differentiatio...

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Detalles Bibliográficos
Autores principales: Bhaskaran, Vivek, Nowicki, Michal O., Idriss, Mahmoud, Jimenez, Miguel A., Lugli, Gianmarco, Hayes, Josie L., Mahmoud, Ahmad Bakur, Zane, Rachel E., Passaro, Carmela, Ligon, Keith L., Haas-Kogan, Daphne, Bronisz, Agnieszka, Godlewski, Jakub, Lawler, Sean E., Chiocca, E. Antonio, Peruzzi, Pierpaolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347618/
https://www.ncbi.nlm.nih.gov/pubmed/30683859
http://dx.doi.org/10.1038/s41467-019-08390-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347618/
https://www.ncbi.nlm.nih.gov/pubmed/30683859
http://dx.doi.org/10.1038/s41467-019-08390-z

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