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Beclin 1 regulates recycling endosome and is required for skin development in mice

Beclin 1 is a key regulator of autophagy and endocytosis. However, its autophagy-independent functions remain poorly understood. Here, we report that Beclin 1 regulates recycling endosome and is required for skin development in vivo. We first established keratinocyte-specific Beclin 1-knockout mice...

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Detalles Bibliográficos
Autores principales: Noguchi, Saori, Honda, Shinya, Saitoh, Tatsuya, Matsumura, Hiroyuki, Nishimura, Emi, Akira, Shizuo, Shimizu, Shigeomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347619/
https://www.ncbi.nlm.nih.gov/pubmed/30701202
http://dx.doi.org/10.1038/s42003-018-0279-0