Histone methyltransferase NSD2 regulates apoptosis and chemosensitivity in osteosarcoma

Osteosarcoma (OS) is a primary malignant bone tumour. However, the genetic basis for the pathogenesis of OS remains elusive. In this study, we uncovered the role of the histone methyltransferase NSD2 in regulating tumourigenesis and chemosensitivity in OS. We show that NSD2 knockdown leads to increa...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Chao, Liu, Chao, Wang, Lei, Sun, Yangbai, Jiang, Yuhang, Hao, Yongqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347630/
https://www.ncbi.nlm.nih.gov/pubmed/30683853
http://dx.doi.org/10.1038/s41419-019-1347-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347630/
https://www.ncbi.nlm.nih.gov/pubmed/30683853
http://dx.doi.org/10.1038/s41419-019-1347-1

Ejemplares similares