Cargando…

SHROOM2 inhibits tumor metastasis through RhoA–ROCK pathway-dependent and -independent mechanisms in nasopharyngeal carcinoma

SHROOM2 is a key mediator of RhoA–ROCK pathway that regulates cell motility and actin cytoskeleton organization. However, the functions of SHROOM2 beyond RhoA/ROCK signaling remain poorly understood. Here, we report that SHROOM2 not only participates in RhoA–ROCK-induced stress fiber formation and f...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Jing, Chen, Lin, Xiao, Jingshu, Qi, Xue-Kang, Zhang, Ji, Li, Xu, Wang, Zifeng, Lian, Yi-Fan, Xiang, Tong, Zhang, Yuchen, Chen, Ming-Yuan, Bei, Jin-Xin, Zeng, Yi-Xin, Feng, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347642/
https://www.ncbi.nlm.nih.gov/pubmed/30683844
http://dx.doi.org/10.1038/s41419-019-1325-7