Cargando…

SHROOM2 inhibits tumor metastasis through RhoA–ROCK pathway-dependent and -independent mechanisms in nasopharyngeal carcinoma

SHROOM2 is a key mediator of RhoA–ROCK pathway that regulates cell motility and actin cytoskeleton organization. However, the functions of SHROOM2 beyond RhoA/ROCK signaling remain poorly understood. Here, we report that SHROOM2 not only participates in RhoA–ROCK-induced stress fiber formation and f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Jing, Chen, Lin, Xiao, Jingshu, Qi, Xue-Kang, Zhang, Ji, Li, Xu, Wang, Zifeng, Lian, Yi-Fan, Xiang, Tong, Zhang, Yuchen, Chen, Ming-Yuan, Bei, Jin-Xin, Zeng, Yi-Xin, Feng, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347642/ https://www.ncbi.nlm.nih.gov/pubmed/30683844 http://dx.doi.org/10.1038/s41419-019-1325-7

Ejemplares similares

Involvement of Histamine and RhoA/ROCK in Penicillin Immediate Hypersensitivity Reactions
por: Han, Jiayin, et al.
Publicado: (2016)

The RhoA-ROCK pathway in the regulation of T and B cell responses
por: Ricker, Edd, et al.
Publicado: (2016)

The Involvement of the RhoA/ROCK Signaling Pathway in Hypersensitivity Reactions Induced by Paclitaxel Injection
por: Pan, Chen, et al.
Publicado: (2019)

RhoA and RhoC Are Both Required for the ROCK II-Dependent Promotion of Centrosome Duplication
por: Kanai, Masayuki, et al.
Publicado: (2010)

AMF siRNA treatment of keloid through inhibition signaling pathway of RhoA/ROCK1
por: Tian, Yi, et al.
Publicado: (2018)

RhoA/ROCK1 regulates Avian Reovirus S1133-induced switch from autophagy to apoptosis
por: Lin, Ping-Yuan, et al.
Publicado: (2015)

A TRANSCRIPTIONAL CROSS–TALK BETWEEN RhoA AND c–Myc INHIBITS THE RhoA/Rock–DEPENDENT CYTOSKELETON
por: Sauzeau, Vincent, et al.
Publicado: (2010)

Activation of RhoA-ROCK-BMP signaling reprograms adult human corneal endothelial cells
por: Zhu, Ying-Ting, et al.
Publicado: (2014)

BMPR2 promotes invasion and metastasis via the RhoA-ROCK-LIMK2 pathway in human osteosarcoma cells
por: Wang, Shidong, et al.
Publicado: (2017)

Acrolein, an endogenous aldehyde induces synaptic dysfunction in vitro and in vivo: Involvement of RhoA/ROCK2 pathway
por: Zhu, Zeyu, et al.
Publicado: (2022)

Mechanism of RhoA regulating benign prostatic hyperplasia: RhoA-ROCK-β-catenin signaling axis and static & dynamic dual roles
por: Shan, Shidong, et al.
Publicado: (2023)

Brusatol Inhibits Proliferation and Metastasis of Colorectal Cancer by Targeting and Reversing the RhoA/ROCK1 Pathway
por: Lu, Rui-jin, et al.
Publicado: (2022)

NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction
por: Zhang, Chao, et al.
Publicado: (2016)

Protocol for structural and biochemical analyses of RhoA GTPase
por: Lin, Yuan, et al.
Publicado: (2021)

Nogo-B promotes invasion and metastasis of nasopharyngeal carcinoma via RhoA-SRF-MRTFA pathway
por: Wang, Jingyi, et al.
Publicado: (2022)

RhoA, ROCK-1, and ROCK-2 Gene Expression and Polymorphisms in Cholesteatoma Patients
por: Görür, Kemal, et al.
Publicado: (2021)

Calcium and TRPV4 promote metastasis by regulating cytoskeleton through the RhoA/ROCK1 pathway in endometrial cancer
por: Li, Xingchen, et al.
Publicado: (2020)

RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock
por: Mikelis, Constantinos M., et al.
Publicado: (2015)

RhoA/ROCK Signaling Pathway Mediates Shuanghuanglian Injection-Induced Pseudo-allergic Reactions
por: Han, Jiayin, et al.
Publicado: (2018)

RhoA suppresses pseudorabies virus replication in vitro
por: Li, Xin-Man, et al.
Publicado: (2023)

Arp2/3-Branched Actin Maintains an Active Pool of GTP-RhoA and Controls RhoA Abundance
por: Huang, Yuxing, et al.
Publicado: (2019)

CapG promoted nasopharyngeal carcinoma cell motility involving Rho motility pathway independent of ROCK
por: Fu, Ying, et al.
Publicado: (2022)

Axon growth inhibition by RhoA/ROCK in the central nervous system
por: Fujita, Yuki, et al.
Publicado: (2014)

ROCK (RhoA/Rho Kinase) in Cardiovascular–Renal Pathophysiology: A Review of New Advancements
por: Seccia, Teresa M., et al.
Publicado: (2020)

RhoA/ROCK pathway mediates the effect of oestrogen on regulating epithelial‐mesenchymal transition and proliferation in endometriosis
por: Huang, Zhi‐Xiong, et al.
Publicado: (2020)

Leptin Activates RhoA/ROCK Pathway to Induce Cytoskeleton Remodeling in Nucleus Pulposus Cells
por: Li, Zheng, et al.
Publicado: (2014)

The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice
por: Das, Debamitra, et al.
Publicado: (2014)

Rho GTPase and Shroom direct planar polarized actomyosin contractility during convergent extension
por: Simões, Sérgio de Matos, et al.
Publicado: (2014)

Roles of the RhoA-ROCK Signaling Pathway in the Endothelial H(2)S Production and Vasodilation in Rat Cerebral Arteries
por: Chen, Shuo, et al.
Publicado: (2022)

The RhoA-ROCK1/ROCK2 Pathway Exacerbates Inflammatory Signaling in Immortalized and Primary Microglia
por: Glotfelty, Elliot J., et al.
Publicado: (2023)

RhoA/ROCK Regulates Prion Pathogenesis by Controlling Connexin 43 Activity
por: Kim, Hee-Jun, et al.
Publicado: (2020)

RhoA-ROCK Signaling as a Therapeutic Target in Traumatic Brain Injury
por: Mulherkar, Shalaka, et al.
Publicado: (2020)

Downregulation of HAS-2 regulates the chondrocyte cytoskeleton and induces cartilage degeneration by activating the RhoA/ROCK signaling pathway
por: Yang, Junlong, et al.
Publicado: (2023)

TAGLN mediated stiffness-regulated ovarian cancer progression via RhoA/ROCK pathway
por: Wei, Xiao, et al.
Publicado: (2021)

MiR-31 Regulates Rho-Associated Kinase-Myosin Light Chain (ROCK-MLC) Pathway and Inhibits Gastric Cancer Invasion: Roles of RhoA
por: Chen, Zhuo, et al.
Publicado: (2016)

ZXDC enhances cervical cancer metastasis through IGF2BP3-mediated activation of RhoA/ROCK signaling
por: Mao, Yifang, et al.
Publicado: (2023)

ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens
por: Priya, Rashmi, et al.
Publicado: (2017)

Osteosarcoma cell intrinsic PD-L2 signals promote invasion and metastasis via the RhoA-ROCK-LIMK2 and autophagy pathways
por: Ren, Tingting, et al.
Publicado: (2019)

Coxiella burnetii Phagocytosis Is Regulated by GTPases of the Rho Family and the RhoA Effectors mDia1 and ROCK
por: Salinas, Romina P., et al.
Publicado: (2015)

RhoA/ROCK-dependent moesin phosphorylation regulates AGE-induced endothelial cellular response
por: Wang, Jiping, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_iaag2c5nbjgvcp7od97cp1j82d