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CKIP-1 limits foam cell formation and inhibits atherosclerosis by promoting degradation of Oct-1 by REGγ

Atherosclerosis-related cardiovascular diseases are the leading cause of mortality worldwide. Macrophages uptake modified lipoproteins and transform into foam cells, triggering an inflammatory response and thereby promoting plaque formation. Here we show that casein kinase 2-interacting protein-1 (C...

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Detalles Bibliográficos
Autores principales: Fan, Jiao, Liu, Lifeng, Liu, Qingyan, Cui, Yu, Yao, Binwei, Zhang, Minghua, Gao, Yabing, Fu, Yesheng, Dai, Hongmiao, Pan, Jingkun, Qiu, Ya, Liu, Cui Hua, He, Fuchu, Wang, Yu, Zhang, Lingqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347643/
https://www.ncbi.nlm.nih.gov/pubmed/30683852
http://dx.doi.org/10.1038/s41467-018-07895-3