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CKIP-1 limits foam cell formation and inhibits atherosclerosis by promoting degradation of Oct-1 by REGγ
Atherosclerosis-related cardiovascular diseases are the leading cause of mortality worldwide. Macrophages uptake modified lipoproteins and transform into foam cells, triggering an inflammatory response and thereby promoting plaque formation. Here we show that casein kinase 2-interacting protein-1 (C...
Autores principales: | Fan, Jiao, Liu, Lifeng, Liu, Qingyan, Cui, Yu, Yao, Binwei, Zhang, Minghua, Gao, Yabing, Fu, Yesheng, Dai, Hongmiao, Pan, Jingkun, Qiu, Ya, Liu, Cui Hua, He, Fuchu, Wang, Yu, Zhang, Lingqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347643/ https://www.ncbi.nlm.nih.gov/pubmed/30683852 http://dx.doi.org/10.1038/s41467-018-07895-3 |
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