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Exosomes from differentially activated macrophages influence dormancy or resurgence of breast cancer cells within bone marrow stroma
Breast cancer (BC) cells (BCCs) can retain cellular quiescence for decades, a phenomenon referred to as dormancy. BCCs show preference for the bone marrow (BM) where they can remain dormant for decades. Targeting BCCs within the BM is a challenge since the dormant BCCs reside within BM stroma, also...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347644/ https://www.ncbi.nlm.nih.gov/pubmed/30683851 http://dx.doi.org/10.1038/s41419-019-1304-z |