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Exosomes from differentially activated macrophages influence dormancy or resurgence of breast cancer cells within bone marrow stroma

Breast cancer (BC) cells (BCCs) can retain cellular quiescence for decades, a phenomenon referred to as dormancy. BCCs show preference for the bone marrow (BM) where they can remain dormant for decades. Targeting BCCs within the BM is a challenge since the dormant BCCs reside within BM stroma, also...

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Detalles Bibliográficos
Autores principales: Walker, Nykia D., Elias, Michael, Guiro, Khadidiatou, Bhatia, Ranvir, Greco, Steven J., Bryan, Margarette, Gergues, Marina, Sandiford, Oleta A., Ponzio, Nicholas M., Leibovich, Samuel J., Rameshwar, Pranela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347644/
https://www.ncbi.nlm.nih.gov/pubmed/30683851
http://dx.doi.org/10.1038/s41419-019-1304-z