Type I interferon response impairs differentiation potential of pluripotent stem cells

Upon virus infection, pluripotent stem cells neither induce nor respond to canonical type I interferons (IFN-I). To better understand this biology, we characterized induced pluripotent stem cells (iPSCs) as well as their differentiated parental or rederived counterparts. We confirmed that only iPSCs...

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Detalles Bibliográficos
Autores principales: Eggenberger, Julie, Blanco-Melo, Daniel, Panis, Maryline, Brennand, Kristen J., tenOever, Benjamin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347712/
https://www.ncbi.nlm.nih.gov/pubmed/30606801
http://dx.doi.org/10.1073/pnas.1812449116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347712/
https://www.ncbi.nlm.nih.gov/pubmed/30606801
http://dx.doi.org/10.1073/pnas.1812449116

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