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Human amnion-derived mesenchymal stem cell (hAD-MSC) transplantation improves ovarian function in rats with premature ovarian insufficiency (POI) at least partly through a paracrine mechanism

BACKGROUND: Chemotherapy can induce premature ovarian insufficiency (POI) and reduce fertility in young female patients. Currently, there is no effective therapy for POI. Human amnion-derived mesenchymal stem cells (hAD-MSCs) may be a promising seed cell for regenerative medicine. This study investi...

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Detalles Bibliográficos
Autores principales: Ling, Li, Feng, Xiushan, Wei, Tianqin, Wang, Yan, Wang, Yaping, Wang, Ziling, Tang, Dongyuan, Luo, Yanjing, Xiong, Zhengai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347748/
https://www.ncbi.nlm.nih.gov/pubmed/30683144
http://dx.doi.org/10.1186/s13287-019-1136-x