Effect of TCF7L2 polymorphism on pancreatic hormones after exenatide in type 2 diabetes

BACKGROUND: Glucagon-like peptide 1 (GLP-1) stimulates insulin secretion and reduces blood glucose in type 2 diabetes mellitus (T2DM). TCF7L2 rs7903146 polymorphism has been associated with decreased insulin secretion, reduced GLP-1 action, and possible impaired peripheral insulin sensitivity. OBJEC...

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Detalles Bibliográficos
Autores principales: Ferreira, Mari Cassol, da Silva, Maria Elizabeth Rossi, Fukui, Rosa Tsuneshiro, do Carmo Arruda-Marques, Maria, Azhar, Salman, dos Santos, Rosa Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347826/
https://www.ncbi.nlm.nih.gov/pubmed/30700996
http://dx.doi.org/10.1186/s13098-019-0401-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347826/
https://www.ncbi.nlm.nih.gov/pubmed/30700996
http://dx.doi.org/10.1186/s13098-019-0401-6

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