Levetiracetam optimal dose-finding as first-line treatment for neonatal seizures occurring in the context of hypoxic-ischaemic encephalopathy (LEVNEONAT-1): study protocol of a phase II trial

INTRODUCTION: Therapeutic schedules for treating neonatal seizures remain elusive. First-line treatment with phenobarbital is widely supported but without strong scientific evidence. Levetiracetam (LEV) is an emerging and promising antiepileptic drug (AED). The aim of this phase II trial is to deter...

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Detalles Bibliográficos
Autores principales: Favrais, Geraldine, Ursino, Moreno, Mouchel, Catherine, Boivin, Estelle, Jullien, Vincent, Zohar, Sarah, Saliba, Elie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Paediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347888/
https://www.ncbi.nlm.nih.gov/pubmed/30679288
http://dx.doi.org/10.1136/bmjopen-2018-022739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347888/
https://www.ncbi.nlm.nih.gov/pubmed/30679288
http://dx.doi.org/10.1136/bmjopen-2018-022739

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