Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability

Epigenetic modifications confer stable transcriptional patterns in the brain and both normal and abnormal brain function involve specialized brain regions. We examined DNA methylation by whole genome bisulfite sequencing in neuronal and non-neuronal populations from four brain regions (anterior cing...

Descripción completa

Detalles Bibliográficos
Autores principales: Rizzardi, Lindsay F., Hickey, Peter F., DiBlasi, Varenka Rodriguez, Tryggvadóttir, Rakel, Callahan, Colin M., Idrizi, Adrian, Hansen, Kasper D., Feinberg, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348048/
https://www.ncbi.nlm.nih.gov/pubmed/30643296
http://dx.doi.org/10.1038/s41593-018-0297-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348048/
https://www.ncbi.nlm.nih.gov/pubmed/30643296
http://dx.doi.org/10.1038/s41593-018-0297-8

Ejemplares similares