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TRAIL-Expressing Monocyte/Macrophages Are Critical for Reducing Inflammation and Atherosclerosis

Circulating tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) levels are reduced in patients with cardiovascular disease, and TRAIL gene deletion in mice exacerbates atherosclerosis and inflammation. How TRAIL protects against atherosclerosis and why levels are reduced in disease...

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Detalles Bibliográficos
Autores principales: Cartland, Siân P., Genner, Scott W., Martínez, Gonzalo J., Robertson, Stacy, Kockx, Maaike, Lin, Ruby CY., O'Sullivan, John F., Koay, Yen Chin, Manuneedhi Cholan, Pradeep, Kebede, Melkam A., Murphy, Andrew J., Masters, Seth, Bennett, Martin R., Jessup, Wendy, Kritharides, Leonard, Geczy, Carolyn, Patel, Sanjay, Kavurma, Mary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348195/
https://www.ncbi.nlm.nih.gov/pubmed/30665196
http://dx.doi.org/10.1016/j.isci.2018.12.037