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Cholesterol and Its Metabolites in Tumor Growth: Therapeutic Potential of Statins in Cancer Treatment

Cholesterol is essential for cell function and viability. It is a component of the plasma membrane and lipid rafts and is a precursor for bile acids, steroid hormones, and Vitamin D. As a ligand for estrogen-related receptor alpha (ESRRA), cholesterol becomes a signaling molecule. Furthermore, chole...

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Detalles Bibliográficos
Autores principales: Chimento, Adele, Casaburi, Ivan, Avena, Paola, Trotta, Francesca, De Luca, Arianna, Rago, Vittoria, Pezzi, Vincenzo, Sirianni, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348274/
https://www.ncbi.nlm.nih.gov/pubmed/30719023
http://dx.doi.org/10.3389/fendo.2018.00807