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The Genomic Health of Human Pluripotent Stem Cells: Genomic Instability and the Consequences on Nuclear Organization

Human pluripotent stem cells (hPSCs) are increasingly used for cell-based regenerative therapies worldwide, with embryonic and induced pluripotent stem cells as potential treatments for debilitating and chronic conditions, such as age-related macular degeneration, Parkinson's disease, spinal co...

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Detalles Bibliográficos
Autores principales: Henry, Marianne P., Hawkins, J. Ross, Boyle, Jennifer, Bridger, Joanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348275/
https://www.ncbi.nlm.nih.gov/pubmed/30719030
http://dx.doi.org/10.3389/fgene.2018.00623