Genome-wide Screen for Culture Adaptation and Tumorigenicity-Related Genes in Human Pluripotent Stem Cells

Human pluripotent stem cells (hPSCs) acquire genetic changes during their propagation in culture that can affect their use in research and future therapies. To identify the key genes involved in selective advantage during culture adaptation and tumorigenicity of hPSCs, we generated a genome-wide scr...

Descripción completa

Detalles Bibliográficos
Autores principales: Weissbein, Uri, Peretz, Mordecai, Plotnik, Omer, Yanuka, Ofra, Sagi, Ido, Golan-Lev, Tamar, Benvenisty, Nissim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348297/
https://www.ncbi.nlm.nih.gov/pubmed/30660107
http://dx.doi.org/10.1016/j.isci.2018.12.031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348297/
https://www.ncbi.nlm.nih.gov/pubmed/30660107
http://dx.doi.org/10.1016/j.isci.2018.12.031

Ejemplares similares